Gene description for TXN
Gene name thioredoxin
Gene symbol TXN
Other names/aliases TRDX
TRX
TRX1
TXN1
Trx80
Species Homo sapiens
 Experiment description of studies that identified TXN in Glioblastoma cells

1
Experiment ID203
Identified moleculemrna
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Microarray
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleGlioblastoma cells
Sample nameGlioblastoma cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
miRNA
mRNA
Methods used in the studyRT-PCR
Antibody array
Microarray
EV-TRACK -

2
Experiment ID1243
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25261722   
OrganismHomo sapiens
Experiment descriptionInflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.
AuthorsKore RA, Abraham EC.
Journal name Biochem Biophys Res Commun.
Publication year2014
SampleGlioblastoma cells
Sample nameU373 cells treated with 10ng/ml of TNF-.
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140183: EV-METRIC:22%

3
Experiment ID1274
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23807490   
OrganismHomo sapiens
Experiment descriptionGlioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells.
AuthorsLi CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, Grau GE, Combes V, Bebawy M, Gong J, Brammah S, Buckland ME, Suter CM.
Journal name RNA Biol.
Publication year2013
SampleGlioblastoma cells
Sample nameU251 cells
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV130098: EV-METRIC:29%

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